The regulation of rat liver xanthine oxidase. Conversion in vitro of the enzyme activity from dehydrogenase (type D) to oxidase (type O).
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چکیده
منابع مشابه
Liver Xanthine Oxidase INVOLVEMENT OF THIOL GROUPS IN THE CONVERSION OF THE ENZYME ACTIVITY FROM DEHYDROGENASE (TYPE D) INTO OXIDASE (TYPE 0) AND PURIFICATION OF THE ENZYME By E. DELLA CORTE and F. STIRPE
1. The 'xanthine oxidase' activity of rat liver supernatant, most of which behaves as an NAD+-dependent dehydrogenase (type D) can be rapidly converted into an oxidase (type 0) by thiol reagents such as tetraethylthiuram disulphide, copper sulphate, 5,5'-dithiobis(2-nitrobenzoic acid), N-ethylmaleimide and p-hydroxymercuribenzoate. Treatment with copper sulphate, if prolonged, leads to almost c...
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عنوان ژورنال:
- The Journal of biological chemistry
دوره 244 14 شماره
صفحات -
تاریخ انتشار 1969